Inhibition of host Ogr1 enhances effector CD8(+) T-cell function by modulating acidic microenvironment

Immunotherapies for cancer, such as immune checkpoint blockade or adoptive T-cell transfer, can lead to a long-lasting clinical response. But the therapeutic response rate remains low on account of many tumors that have evolved sophisticated strategies to evade immune surveillance. Solid tumors are...

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Detalles Bibliográficos
Autores principales: Cao, Lin, Li, Weisha, Yang, Xingjiu, Zhang, Wenlong, Li, Mengyuan, Zhang, Haizeng, Qin, Chuan, Chen, Xiaohong, Gao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571096/
https://www.ncbi.nlm.nih.gov/pubmed/34158625
http://dx.doi.org/10.1038/s41417-021-00354-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571096/
https://www.ncbi.nlm.nih.gov/pubmed/34158625
http://dx.doi.org/10.1038/s41417-021-00354-0

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