Membrane-Bound MMP-14 Protease-Activatable Adeno-Associated Viral Vectors for Gene Delivery to Pancreatic Tumors

Adeno-associated virus’ (AAV) relatively simple structure makes it accommodating for engineering into controllable delivery platforms. Cancer, such as pancreatic ductal adenocarcinoma (PDAC), are often characterized by upregulation of membrane-bound proteins, such as MMP-14, that propagate survival...

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Detalles Bibliográficos
Autores principales: Butler, Susan S, Date, Kenjiro, Okumura, Takashi, Lueck, Cooper, Ghosh, Bidyut, Maitra, Anirban, Suh, Junghae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571120/
https://www.ncbi.nlm.nih.gov/pubmed/33958732
http://dx.doi.org/10.1038/s41434-021-00255-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571120/
https://www.ncbi.nlm.nih.gov/pubmed/33958732
http://dx.doi.org/10.1038/s41434-021-00255-9

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