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Exhaustion in tumor-infiltrating Mucosal-Associated Invariant T (MAIT) cells from colon cancer patients

Mucosal-associated invariant T (MAIT) cells are unconventional T cells recognizing microbial metabolites, presented by the invariant MR1 protein. Upon activation, MAIT cells rapidly secrete cytokines and exert cytotoxic functions, and may thus be highly relevant also in tumor immunity. MAIT cells ac...

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Detalles Bibliográficos
Autores principales: Rodin, William, Sundström, Patrik, Ahlmanner, Filip, Szeponik, Louis, Zajt, Kamil Kajetan, Wettergren, Yvonne, Bexe Lindskog, Elinor, Quiding Järbrink, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571139/
https://www.ncbi.nlm.nih.gov/pubmed/33885944
http://dx.doi.org/10.1007/s00262-021-02939-y