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CD38 identifies pre-activated CD8+ T cells which can be reinvigorated by anti-PD-1 blockade in human lung cancer

BACKGROUND: CD38 has been observed expressing in activated T cells, while the features and functions of CD38+ T cells in human NSCLC are still unclear. METHODS: Here we uncovered the correlation between CD38 expression and survival and immune infiltration levels in tumor of NSCLC. Then, we collected...

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Detalles Bibliográficos
Autores principales: Wu, Pin, Zhao, Lufeng, Chen, Yongyuan, Xin, Zhongwei, Lin, Mingjie, Hao, Zhixing, Chen, Xiaoke, Chen, Di, Wu, Dang, Chai, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571140/
https://www.ncbi.nlm.nih.gov/pubmed/33934206
http://dx.doi.org/10.1007/s00262-021-02949-w