Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis

Metastasis is a fatal disease where research progress has been hindered by a lack of authentic experimental models. Here, we develop a 3D tumor sphere culture-transplant system that facilitates the growth and engineering of patient-derived xenograft (PDX) tumor cells for functional metastasis assays...

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Detalles Bibliográficos
Autores principales: Ma, Dennis, Hernandez, Grace A., Lefebvre, Austin E. Y. T., Alshetaiwi, Hamad, Blake, Kerrigan, Dave, Kushal R., Rauf, Maha, Williams, Justice W., Davis, Ryan T., Evans, Katrina T., Longworth, Aaron, Masoud, Madona Y. G., Lee, Regis, Edwards, Robert A., Digman, Michelle A., Kessenbrock, Kai, Lawson, Devon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571269/
https://www.ncbi.nlm.nih.gov/pubmed/34741115
http://dx.doi.org/10.1038/s42003-021-02596-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571269/
https://www.ncbi.nlm.nih.gov/pubmed/34741115
http://dx.doi.org/10.1038/s42003-021-02596-y

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