Cargando…
Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis
Metastasis is a fatal disease where research progress has been hindered by a lack of authentic experimental models. Here, we develop a 3D tumor sphere culture-transplant system that facilitates the growth and engineering of patient-derived xenograft (PDX) tumor cells for functional metastasis assays...
Autores principales: | Ma, Dennis, Hernandez, Grace A., Lefebvre, Austin E. Y. T., Alshetaiwi, Hamad, Blake, Kerrigan, Dave, Kushal R., Rauf, Maha, Williams, Justice W., Davis, Ryan T., Evans, Katrina T., Longworth, Aaron, Masoud, Madona Y. G., Lee, Regis, Edwards, Robert A., Digman, Michelle A., Kessenbrock, Kai, Lawson, Devon A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571269/ https://www.ncbi.nlm.nih.gov/pubmed/34741115 http://dx.doi.org/10.1038/s42003-021-02596-y |
Ejemplares similares
-
Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release
por: Egea, Virginia, et al.
Publicado: (2021) -
Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity
por: Nguyen, Quy H., et al.
Publicado: (2018) -
Collagen density modulates triple-negative breast cancer cell metabolism through adhesion-mediated contractility
por: Mah, Emma J., et al.
Publicado: (2018) -
Exosome loaded immunomodulatory biomaterials alleviate local immune response in immunocompetent diabetic mice post islet xenotransplantation
por: Mohammadi, M. Rezaa, et al.
Publicado: (2021) -
Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers
por: Takai, Ken, et al.
Publicado: (2018)