Crosstalk between CST and RPA regulates RAD51 activity during replication stress

Replication stress causes replication fork stalling, resulting in an accumulation of single-stranded DNA (ssDNA). Replication protein A (RPA) and CTC1-STN1-TEN1 (CST) complex bind ssDNA and are found at stalled forks, where they regulate RAD51 recruitment and foci formation in vivo. Here, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, Kai-Hang, Yang, Han-Lin, Chang, Hao-Yen, Yeh, Hsin-Yi, Nguyen, Dinh Duc, Lee, Tzu-Yu, Lyu, Xinxing, Chastain, Megan, Chai, Weihang, Li, Hung-Wen, Chi, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571288/
https://www.ncbi.nlm.nih.gov/pubmed/34741010
http://dx.doi.org/10.1038/s41467-021-26624-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571288/
https://www.ncbi.nlm.nih.gov/pubmed/34741010
http://dx.doi.org/10.1038/s41467-021-26624-x

Ejemplares similares