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Transcriptional inhibition by CDK7/9 inhibitor SNS-032 suppresses tumor growth and metastasis in esophageal squamous cell carcinoma

Metastasis is one of most lethal causes that confer a poor prognosis of patients with esophageal squamous cell carcinoma (ESCC), whereas there is no available target drug for metastatic ESCC currently. In this study, we aimed to determine whether the transcriptional inhibition by CDK7/9 inhibitor SN...

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Detalles Bibliográficos
Autores principales: Zeng, Huishan, Yang, Huiru, Song, Yifan, Fang, Dong, Chen, Liang, Zhao, Zhijun, Wang, Chaojie, Xie, Songqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571299/
https://www.ncbi.nlm.nih.gov/pubmed/34741018
http://dx.doi.org/10.1038/s41419-021-04344-w