Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2

Mitochondrial mass imbalance is one of the key causes of cardiovascular dysfunction after hypoxia. The activation of dynamin-related protein 1 (Drp1), as well as its mitochondrial translocation, play important roles in the changes of both mitochondrial morphology and mitochondrial functions after hy...

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Detalles Bibliográficos
Autores principales: Duan, Chenyang, Kuang, Lei, Hong, Chen, Xiang, Xinming, Liu, Jiancang, Li, Qinghui, Peng, Xiaoyong, Zhou, Yuanqun, Wang, Hongchen, Liu, Liangming, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571301/
https://www.ncbi.nlm.nih.gov/pubmed/34741026
http://dx.doi.org/10.1038/s41419-021-04343-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571301/
https://www.ncbi.nlm.nih.gov/pubmed/34741026
http://dx.doi.org/10.1038/s41419-021-04343-x

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