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Mitochondrial Drp1 recognizes and induces excessive mPTP opening after hypoxia through BAX-PiC and LRRK2-HK2
Mitochondrial mass imbalance is one of the key causes of cardiovascular dysfunction after hypoxia. The activation of dynamin-related protein 1 (Drp1), as well as its mitochondrial translocation, play important roles in the changes of both mitochondrial morphology and mitochondrial functions after hy...
Autores principales: | Duan, Chenyang, Kuang, Lei, Hong, Chen, Xiang, Xinming, Liu, Jiancang, Li, Qinghui, Peng, Xiaoyong, Zhou, Yuanqun, Wang, Hongchen, Liu, Liangming, Li, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571301/ https://www.ncbi.nlm.nih.gov/pubmed/34741026 http://dx.doi.org/10.1038/s41419-021-04343-x |
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