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Massively parallel interrogation of protein fragment secretability using SECRiFY reveals features influencing secretory system transit

While transcriptome- and proteome-wide technologies to assess processes in protein biogenesis are now widely available, we still lack global approaches to assay post-ribosomal biogenesis events, in particular those occurring in the eukaryotic secretory system. We here develop a method, SECRiFY, to s...

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Detalles Bibliográficos
Autores principales: Boone, Morgane, Ramasamy, Pathmanaban, Zuallaert, Jasper, Bouwmeester, Robbin, Van Moer, Berre, Maddelein, Davy, Turan, Demet, Hulstaert, Niels, Eeckhaut, Hannah, Vandermarliere, Elien, Martens, Lennart, Degroeve, Sven, De Neve, Wesley, Vranken, Wim, Callewaert, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571348/
https://www.ncbi.nlm.nih.gov/pubmed/34741024
http://dx.doi.org/10.1038/s41467-021-26720-y