Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles

The pathogenesis of type 2 diabetes (T2D) might change with increasing age. Here, we used a stratification based on age of diagnosis to gain insight into the genetics and causal risk factors of T2D across different age-groups. We performed genome-wide association studies (GWAS) on T2D and T2D subgro...

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Detalles Bibliográficos
Autores principales: Noordam, Raymond, Läll, Kristi, Smit, Roelof A.J., Laisk, Triin, Metspalu, Andres, Esko, Tõnu, Milani, Lili, Loos, Ruth J.F., Mägi, Reedik, Willems van Dijk, Ko, van Heemst, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571356/
https://www.ncbi.nlm.nih.gov/pubmed/33972266
http://dx.doi.org/10.2337/db20-0602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571356/
https://www.ncbi.nlm.nih.gov/pubmed/33972266
http://dx.doi.org/10.2337/db20-0602

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