S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis

Autism Spectrum Disorders (ASD) are caused by a combination of genetic predisposition and nongenetic factors. Among the nongenetic factors, maternal immune system activation and zinc deficiency have been proposed. Intriguingly, as a genetic factor, copy-number variations in S100B, a pro-inflammatory...

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Detalles Bibliográficos
Autores principales: Daini, Eleonora, Hagmeyer, Simone, De Benedictis, Chiara A., Cristóvão, Joana S., Bodria, Martina, Ross, Aisling M., Raab, Andrea, Boeckers, Tobias M., Feldmann, Joerg, Gomes, Cláudio M., Zoli, Michele, Vilella, Antonietta, Grabrucker, Andreas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571423/
https://www.ncbi.nlm.nih.gov/pubmed/34741005
http://dx.doi.org/10.1038/s41398-021-01694-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571423/
https://www.ncbi.nlm.nih.gov/pubmed/34741005
http://dx.doi.org/10.1038/s41398-021-01694-z

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