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How many markers are needed to robustly determine a cell's type?

Our understanding of cell types has advanced considerably with the publication of single-cell atlases. Marker genes play an essential role for experimental validation and computational analyses such as physiological characterization, annotation, and deconvolution. However, a framework for quantifyin...

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Detalles Bibliográficos
Autores principales: Fischer, Stephan, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571500/
https://www.ncbi.nlm.nih.gov/pubmed/34765918
http://dx.doi.org/10.1016/j.isci.2021.103292