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Molecular dynamics simulations elucidate oligosaccharide recognition pathways by galectin-3 at atomic resolution

The recognition of carbohydrates by lectins plays key roles in diverse cellular processes such as cellular adhesion, proliferation, and apoptosis, which makes it a therapeutic target of significance against cancers. One of the most functionally active lectins, galectin-3 is distinctively known for i...

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Detalles Bibliográficos
Autores principales: Koneru, Jaya Krishna, Sinha, Suman, Mondal, Jagannath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571523/
https://www.ncbi.nlm.nih.gov/pubmed/34619151
http://dx.doi.org/10.1016/j.jbc.2021.101271