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Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest

Melanoma is an aggressive skin cancer that metastasizes to other organs. While immune checkpoint blockade with anti-PD-1 has transformed the treatment of advanced melanoma, many melanoma patients fail to respond to anti-PD-1 therapy or develop acquired resistance. Thus, effective treatment of melano...

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Detalles Bibliográficos
Autores principales: Adams, Anngela C., Macy, Anne M., Kang, Paul, Castro-Ochoa, Karla F., Wijeratne, E.M. Kithsiri, Xu, Ya-Ming, Liu, Manping X., Charos, Alexandra, Bosenberg, Marcus W., Gunatilaka, A.A. Leslie, Sertil, Aparna R., Hastings, K. Taraszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571524/
https://www.ncbi.nlm.nih.gov/pubmed/34735896
http://dx.doi.org/10.1016/j.tranon.2021.101259