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Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest
Melanoma is an aggressive skin cancer that metastasizes to other organs. While immune checkpoint blockade with anti-PD-1 has transformed the treatment of advanced melanoma, many melanoma patients fail to respond to anti-PD-1 therapy or develop acquired resistance. Thus, effective treatment of melano...
Autores principales: | Adams, Anngela C., Macy, Anne M., Kang, Paul, Castro-Ochoa, Karla F., Wijeratne, E.M. Kithsiri, Xu, Ya-Ming, Liu, Manping X., Charos, Alexandra, Bosenberg, Marcus W., Gunatilaka, A.A. Leslie, Sertil, Aparna R., Hastings, K. Taraszka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571524/ https://www.ncbi.nlm.nih.gov/pubmed/34735896 http://dx.doi.org/10.1016/j.tranon.2021.101259 |
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