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Detection of glucose-derived d- and l-lactate in cancer cells by the use of a chiral NMR shift reagent
BACKGROUND: Excessive lactate production, a hallmark of cancer, is largely formed by the reduction of pyruvate via lactate dehydrogenase (LDH) to l-lactate. Although d-lactate can also be produced from glucose via the methylglyoxal pathway in small amounts, less is known about the amount of d-lactat...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571830/ https://www.ncbi.nlm.nih.gov/pubmed/34742347 http://dx.doi.org/10.1186/s40170-021-00267-4 |