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Chromosomal integration of Tn5253 occurs downstream of a conserved 11-bp sequence of the rbgA gene in Streptococcus pneumoniae and in all the other known hosts of this integrative conjugative element (ICE)

BACKGROUND: Tn5253, a composite Integrative Conjugative Element (ICE) of Streptococcus pneumoniae carrying tet(M) and cat resistance determinants, was found to (i) integrate at specific 83-bp integration site (attB), (ii) produce circular forms joined by a 84-bp sequence (attTn), and (iii) restore t...

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Detalles Bibliográficos
Autores principales: Santoro, Francesco, Fox, Valeria, Romeo, Alessandra, Lazzeri, Elisa, Pozzi, Gianni, Iannelli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571831/
https://www.ncbi.nlm.nih.gov/pubmed/34740368
http://dx.doi.org/10.1186/s13100-021-00253-z