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The balance between AIM2-associated inflammation and autophagy: the role of CHMP2A in brain injury after cardiac arrest

BACKGROUND: Activation of the absent in melanoma 2 (AIM2) inflammasome and impaired autophagosome clearance in neurons contribute significantly to cardiac arrest and return of spontaneous circulation (CA-ROSC) injury, while the mechanism by which the AIM2 inflammasome is regulated and relationship b...

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Detalles Bibliográficos
Autores principales: Shao, Rongjiao, Wang, Xintao, Xu, Tianhua, Xia, Yiyang, Cui, Derong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571899/
https://www.ncbi.nlm.nih.gov/pubmed/34740380
http://dx.doi.org/10.1186/s12974-021-02307-8