Cargando…
The balance between AIM2-associated inflammation and autophagy: the role of CHMP2A in brain injury after cardiac arrest
BACKGROUND: Activation of the absent in melanoma 2 (AIM2) inflammasome and impaired autophagosome clearance in neurons contribute significantly to cardiac arrest and return of spontaneous circulation (CA-ROSC) injury, while the mechanism by which the AIM2 inflammasome is regulated and relationship b...
Autores principales: | Shao, Rongjiao, Wang, Xintao, Xu, Tianhua, Xia, Yiyang, Cui, Derong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8571899/ https://www.ncbi.nlm.nih.gov/pubmed/34740380 http://dx.doi.org/10.1186/s12974-021-02307-8 |
Ejemplares similares
-
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1
por: Deng, Xue, et al.
Publicado: (2021) -
The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization
por: Alqabandi, Maryam, et al.
Publicado: (2021) -
Association of CHMP4B and Autophagy with Micronuclei: Implications for Cataract Formation
por: Sagona, Antonia P., et al.
Publicado: (2014) -
Effects of the Incidence Density of Fever (IDF) on Patients Resuscitated From In-Hospital Cardiac Arrest: A Mediation Analysis
por: Hu, Yue, et al.
Publicado: (2020) -
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
por: Takahashi, Yoshinori, et al.
Publicado: (2018)