Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-d]Pyridazinone Exert Anti-Inflammatory Activity without Acute Gastrotoxicity in the Carrageenan-Induced Rat Paw Edema Test

BACKGROUND AND PURPOSE: Due to the risk of gastrointestinal damage and various tissue toxicity associated with non-steroidal anti-inflammatory drugs (NSAIDs) use, investigating new anti-inflammatory agents with efficacy comparable to that of NSAIDs but reduced toxicity is still a major challenge and...

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Detalles Bibliográficos
Autores principales: Szandruk-Bender, Marta, Merwid-Ląd, Anna, Wiatrak, Benita, Danielewski, Maciej, Dzimira, Stanisław, Szkudlarek, Danuta, Szczukowski, Łukasz, Świątek, Piotr, Szeląg, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572108/
https://www.ncbi.nlm.nih.gov/pubmed/34754217
http://dx.doi.org/10.2147/JIR.S330614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572108/
https://www.ncbi.nlm.nih.gov/pubmed/34754217
http://dx.doi.org/10.2147/JIR.S330614

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