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Efficacy of anti-TNF dosing interval lengthening in adolescents and young adults with inflammatory bowel disease in sustained remission (FREE-study): protocol for a partially randomised patient preference trial

INTRODUCTION: Anti-tumour necrosis factor (TNF) therapy has greatly improved treatment outcomes in patients with inflammatory bowel disease (IBD), but long-term use is associated with cutaneous reactions, susceptibility to infections and frequent injections or hospital visits. Several non-controlled...

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Detalles Bibliográficos
Autores principales: Bouhuys, Marleen, Lexmond, Willem S, Dijkstra, Gerard, Lobatón, Triana, Louis, Edouard, van Biervliet, Stephanie, Groen, Henk, Guardiola, Jordi, van Rheenen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572401/
https://www.ncbi.nlm.nih.gov/pubmed/34732500
http://dx.doi.org/10.1136/bmjopen-2021-054154