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High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease

Alpha-synuclein seed amplification assays (αSyn-SAAs) are promising diagnostic tools for Parkinson’s disease (PD) and related synucleinopathies. They enable detection of seeding-competent alpha-synuclein aggregates in living patients and have shown high diagnostic accuracy in several PD and other sy...

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Detalles Bibliográficos
Autores principales: Russo, Marco J., Orru, Christina D., Concha-Marambio, Luis, Giaisi, Simone, Groveman, Bradley R., Farris, Carly M., Holguin, Bret, Hughson, Andrew G., LaFontant, David-Erick, Caspell-Garcia, Chelsea, Coffey, Christopher S., Mollon, Jennifer, Hutten, Samantha J., Merchant, Kalpana, Heym, Roland G., Soto, Claudio, Caughey, Byron, Kang, Un Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572469/
https://www.ncbi.nlm.nih.gov/pubmed/34742348
http://dx.doi.org/10.1186/s40478-021-01282-8