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Recent Updates of Natural and Synthetic URAT1 Inhibitors and Novel Screening Methods

Human urate anion transporter 1 (hURAT1) is responsible for the reabsorption of uric acid in the proximal renal tubules and is a promising therapeutic target for treating hyperuricemia. To mitigate the side effects of URAT1-targeted clinical agents such as benzbromarone, there is significant interes...

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Detalles Bibliográficos
Autores principales: Chen, Ying, You, Ruya, Wang, Ke, Wang, Yousheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572588/
https://www.ncbi.nlm.nih.gov/pubmed/34754317
http://dx.doi.org/10.1155/2021/5738900