Cargando…

Acid-base and lipophilic properties of peptide nucleic acid derivatives

The first combined experimental and theoretical study on the ionization and lipophilic properties of peptide nucleic acid (PNA) derivatives, including eleven PNA monomers and two PNA decamers, is described. The acidity constants (pK(a)) of individual acidic and basic centers of PNA monomers were mea...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakare, Pramod, Vasile, Francesca, Vallaro, Maura, Visentin, Sonja, Caron, Giulia, Licandro, Emanuela, Cauteruccio, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572665/
https://www.ncbi.nlm.nih.gov/pubmed/34765277
http://dx.doi.org/10.1016/j.jpha.2020.07.007