Capsid destabilization and epitope alterations of human papillomavirus 18 in the presence of thimerosal

Thimerosal has been widely used as a preservative in drug and vaccine products for decades. Due to the strong propensity to modify thiols in proteins, conformational changes could occur due to covalent bond formation between ethylmercury (a degradant of thimerosal) and thiols. Such a conformational...

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Detalles Bibliográficos
Autores principales: Huang, Xiaofen, Li, Yike, Nie, Meifeng, Yue, Mingxi, Li, Yufang, Lin, Zhijie, Pan, Huirong, Fang, Mujin, Wu, Ting, Li, Shaowei, Zhang, Jun, Xia, Ningshao, Zhao, Qinjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572666/
https://www.ncbi.nlm.nih.gov/pubmed/34765275
http://dx.doi.org/10.1016/j.jpha.2020.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572666/
https://www.ncbi.nlm.nih.gov/pubmed/34765275
http://dx.doi.org/10.1016/j.jpha.2020.08.007

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