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Capsid destabilization and epitope alterations of human papillomavirus 18 in the presence of thimerosal
Thimerosal has been widely used as a preservative in drug and vaccine products for decades. Due to the strong propensity to modify thiols in proteins, conformational changes could occur due to covalent bond formation between ethylmercury (a degradant of thimerosal) and thiols. Such a conformational...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Xi'an Jiaotong University
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572666/ https://www.ncbi.nlm.nih.gov/pubmed/34765275 http://dx.doi.org/10.1016/j.jpha.2020.08.007 |