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Simulation of the oxidative metabolization pattern of netupitant, an NK(1) receptor antagonist, by electrochemistry coupled to mass spectrometry

Considering the frequent use of netupitant in polytherapy, the elucidation of its oxidative metabolization pattern is of major importance. However, there is a lack of published research on the redox behavior of this novel neurokinin-1 receptor antagonist. Therefore, this study was performed to simul...

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Detalles Bibliográficos
Autores principales: Chira, Ruxandra, Fangmeyer, Jens, Neaga, Ioan O., Zaharia, Valentin, Karst, Uwe, Bodoki, Ede, Oprean, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572700/
https://www.ncbi.nlm.nih.gov/pubmed/34765280
http://dx.doi.org/10.1016/j.jpha.2021.03.011