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One extraction tool for in vitro-in vivo extrapolation? SPME-based metabolomics of in vitro 2D, 3D, and in vivo mouse melanoma models

Solid phase microextraction (SPME) in combination with high-resolution mass spectrometry was employed for the determination of metabolomic profile of mouse melanoma growth within in vitro 2D, in vitro 3D, and in vivo models. Such multi-model approach had never been investigated before. Due to the lo...

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Detalles Bibliográficos
Autores principales: Jaroch, Karol, Taczyńska, Paulina, Czechowska, Marta, Bogusiewicz, Joanna, Łuczykowski, Kamil, Burlikowska, Katarzyna, Bojko, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572711/
https://www.ncbi.nlm.nih.gov/pubmed/34765281
http://dx.doi.org/10.1016/j.jpha.2021.03.005