H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity

The developmental role of histone H3K9 methylation (H3K9me), which typifies heterochromatin, remains unclear. In Caenorhabditis elegans, loss of H3K9me leads to a highly divergent upregulation of genes with tissue and developmental-stage specificity. During development H3K9me is lost from differenti...

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Detalles Bibliográficos
Autores principales: Methot, Stephen P., Padeken, Jan, Brancati, Giovanna, Zeller, Peter, Delaney, Colin E., Gaidatzis, Dimos, Kohler, Hubertus, van Oudenaarden, Alexander, Großhans, Helge, Gasser, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572725/
https://www.ncbi.nlm.nih.gov/pubmed/34737442
http://dx.doi.org/10.1038/s41556-021-00776-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572725/
https://www.ncbi.nlm.nih.gov/pubmed/34737442
http://dx.doi.org/10.1038/s41556-021-00776-w

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