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Aucubin prevents steroid‐induced osteoblast apoptosis by enhancing autophagy via AMPK activation

Steroid‐induced osteoblast apoptosis is a crucial pathological process in steroid‐induced osteonecrosis of the femoral head (SONFH). Autophagy can resist apoptosis and AMPK plays an important role in autophagy regulation. Aucubin from the small tree Eucommia ulmoides Oliv., which has a long history...

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Detalles Bibliográficos
Autores principales: Yue, Chen, Jin, Hongting, Zhang, Xue, Li, Wuyin, Wang, Deli, Tong, Peijian, Liu, Youwen, Tan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572759/
https://www.ncbi.nlm.nih.gov/pubmed/34612603
http://dx.doi.org/10.1111/jcmm.16954