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Apatinib inhibits the growth of small cell lung cancer via a mechanism mediated by VEGF, PI3K/Akt and Ki‐67/CD31

This study aimed to investigate the anti‐tumour effect of apatinib on extensive‐stage small cell lung cancer (SCLC) and elucidate the associated mechanisms. NCI‐H345 cells were selected as model cells because of high expression of vascular endothelial growth factor (VEGF), VEGF receptor 2 (VEGFR2) a...

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Detalles Bibliográficos
Autores principales: Zhong, Ning, Zhuang, Wei, Huang, Qian, Wang, Qiang, Jin, Wenjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572765/
https://www.ncbi.nlm.nih.gov/pubmed/34590406
http://dx.doi.org/10.1111/jcmm.16926