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DHFR silence alleviated the development of liver fibrosis by affecting the crosstalk between hepatic stellate cells and macrophages

Liver fibrogenesis is a dynamic cellular and tissue process which has the potential to progress into cirrhosis of even liver cancer and liver failure. The activation of hepatic stellate cells (HSCs) is the central event underlying liver fibrosis. Besides, hepatic macrophages have been proposed as po...

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Detalles Bibliográficos
Autores principales: Peng, Yu, Li, Zedong, Chen, Sheng, Zhou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572769/
https://www.ncbi.nlm.nih.gov/pubmed/34626074
http://dx.doi.org/10.1111/jcmm.16935