Dexmedetomidine alleviates hepatic ischaemia‐reperfusion injury via the PI3K/AKT/Nrf2‐NLRP3 pathway

Hepatic ischaemia‐reperfusion (I/R) injury constitutes a tough difficulty in liver surgery. Dexmedetomidine (Dex) plays a protective role in I/R injury. This study investigated protective mechanism of Dex in hepatic I/R injury. The human hepatocyte line L02 received hypoxia/reoxygenation (H/R) treat...

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Detalles Bibliográficos
Autores principales: Wu, Yan, Qiu, Gaolin, Zhang, Hainie, Zhu, Leilei, Cheng, Gao, Wang, Yiqiao, Li, Yuanhai, Wu, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572787/
https://www.ncbi.nlm.nih.gov/pubmed/34664412
http://dx.doi.org/10.1111/jcmm.16871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572787/
https://www.ncbi.nlm.nih.gov/pubmed/34664412
http://dx.doi.org/10.1111/jcmm.16871

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