The influence of MTHFR genetic polymorphisms on methotrexate therapy in pediatric acute lymphoblastic leukemia

MTHFR is a crucial enzyme in folate metabolism. This study aimed to determine the relationship between MTHFR genetic polymorphism and elimination and toxicities of methotrexate (MTX). To do that, the study enrolled 145 patients diagnosed with acute lymphoblastic leukemia, who received chemotherapy f...

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Detalles Bibliográficos
Autores principales: Shen, Yaqing, Wang, Zhujun, Zhou, Fen, Jin, Runming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572804/
https://www.ncbi.nlm.nih.gov/pubmed/34761111
http://dx.doi.org/10.1515/biol-2021-0121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572804/
https://www.ncbi.nlm.nih.gov/pubmed/34761111
http://dx.doi.org/10.1515/biol-2021-0121

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