Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases

BACKGROUND: The insulin/IGF-1 signaling pathway has a major role in the regulation of longevity both in Caenorhabditis elegans and mammalian species, i.e., reduced activity of this pathway extends lifespan, whereas increased activity accelerates the aging process. The insulin/IGF-1 pathway controls...

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Detalles Bibliográficos
Autores principales: Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572812/
https://www.ncbi.nlm.nih.gov/pubmed/34476533
http://dx.doi.org/10.1007/s00011-021-01498-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572812/
https://www.ncbi.nlm.nih.gov/pubmed/34476533
http://dx.doi.org/10.1007/s00011-021-01498-3

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