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Functional megalin is expressed in renal cysts in a mouse model of adult polycystic kidney disease
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the progressive growth of cysts and a decline of renal function. The clinical feasibility of the number of potential disease-modifying drugs is limited by systemic adverse effects. We hypothesize that megalin, a mul...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572980/ https://www.ncbi.nlm.nih.gov/pubmed/34754438 http://dx.doi.org/10.1093/ckj/sfab088 |