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Functional megalin is expressed in renal cysts in a mouse model of adult polycystic kidney disease

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the progressive growth of cysts and a decline of renal function. The clinical feasibility of the number of potential disease-modifying drugs is limited by systemic adverse effects. We hypothesize that megalin, a mul...

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Detalles Bibliográficos
Autores principales:	Nielsen, Marlene L, Mundt, Mia C, Lildballe, Dorte L, Rasmussen, Maria, Sunde, Lone, Torres, Vicente E, Harris, Peter C, Birn, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8572980/ https://www.ncbi.nlm.nih.gov/pubmed/34754438 http://dx.doi.org/10.1093/ckj/sfab088

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