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Prioritisation of Candidate Genes Underpinning COVID-19 Host Genetic Traits Based on High-Resolution 3D Chromosomal Topology

Genetic variants showing associations with specific biological traits and diseases detected by genome-wide association studies (GWAS) commonly map to non-coding DNA regulatory regions. Many of these regions are located considerable distances away from the genes they regulate and come into their prox...

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Detalles Bibliográficos
Autores principales: Thiecke, Michiel J., Yang, Emma J., Burren, Oliver S., Ray-Jones, Helen, Spivakov, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573080/
https://www.ncbi.nlm.nih.gov/pubmed/34759959
http://dx.doi.org/10.3389/fgene.2021.745672