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Prioritisation of Candidate Genes Underpinning COVID-19 Host Genetic Traits Based on High-Resolution 3D Chromosomal Topology
Genetic variants showing associations with specific biological traits and diseases detected by genome-wide association studies (GWAS) commonly map to non-coding DNA regulatory regions. Many of these regions are located considerable distances away from the genes they regulate and come into their prox...
Autores principales: | Thiecke, Michiel J., Yang, Emma J., Burren, Oliver S., Ray-Jones, Helen, Spivakov, Mikhail |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573080/ https://www.ncbi.nlm.nih.gov/pubmed/34759959 http://dx.doi.org/10.3389/fgene.2021.745672 |
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