Single-cell RNA sequencing reveals a strong connection between Gadd45g upregulation and oncolytic HSV infection in tumor tissue

The oncolytic effect of virotherapy derives from the intrinsic capability of the applied virus in selectively infecting and killing tumor cells. Although oncolytic viruses of various constructions have been shown to efficiently infect and kill tumor cells in vitro, the efficiency of these viruses to...

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Detalles Bibliográficos
Autores principales: Ravirala, Divya, Pei, Guangsheng, Zhao, Zhongming, Zhang, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573104/
https://www.ncbi.nlm.nih.gov/pubmed/34786476
http://dx.doi.org/10.1016/j.omto.2021.10.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573104/
https://www.ncbi.nlm.nih.gov/pubmed/34786476
http://dx.doi.org/10.1016/j.omto.2021.10.006

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