Cargando…
Single-cell RNA sequencing reveals a strong connection between Gadd45g upregulation and oncolytic HSV infection in tumor tissue
The oncolytic effect of virotherapy derives from the intrinsic capability of the applied virus in selectively infecting and killing tumor cells. Although oncolytic viruses of various constructions have been shown to efficiently infect and kill tumor cells in vitro, the efficiency of these viruses to...
Autores principales: | Ravirala, Divya, Pei, Guangsheng, Zhao, Zhongming, Zhang, Xiaoliu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573104/ https://www.ncbi.nlm.nih.gov/pubmed/34786476 http://dx.doi.org/10.1016/j.omto.2021.10.006 |
Ejemplares similares
-
Co-delivery of novel bispecific and trispecific engagers by an amplicon vector augments the therapeutic effect of an HSV-based oncolytic virotherapy
por: Ravirala, Divya, et al.
Publicado: (2021) -
Current strategies in engaging oncolytic viruses with antitumor immunity
por: Boagni, Drew Ashton, et al.
Publicado: (2021) -
oHSV-P10 reduces glioma stem cell enrichment after oncolytic HSV therapy
por: Sahu, Upasana, et al.
Publicado: (2023) -
Gadd45β and Gadd45γ are critical for regulating autoimmunity
por: Liu, Lin, et al.
Publicado: (2005) -
4-Methoxydalbergione Elicits Anticancer Effects by Upregulation of GADD45G in Human Liver Cancer Cells
por: Zeng, Liping, et al.
Publicado: (2023)