Augmented Liver Uptake of the Membrane Voltage Sensor Tetraphenylphosphonium Distinguishes Early Fibrosis in a Mouse Model

Mitochondrial (mito-) oxidative phosphorylation (OxPhos) is a critical determinant of cellular membrane potential/voltage. Dysregulation of OxPhos is a biochemical signature of advanced liver fibrosis. However, less is known about the net voltage of the liver in fibrosis. In this study, using the ra...

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Detalles Bibliográficos
Autores principales: Pandita, Himanshi, Mezey, Esteban, Ganapathy-Kanniappan, Shanmugasundaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573124/
https://www.ncbi.nlm.nih.gov/pubmed/34759830
http://dx.doi.org/10.3389/fphys.2021.676722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573124/
https://www.ncbi.nlm.nih.gov/pubmed/34759830
http://dx.doi.org/10.3389/fphys.2021.676722

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