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Aged IRF3-KO Mice are Protected from Sepsis

PURPOSE: Sepsis is a leading cause of hospital admissions and deaths. Older adults (>65 years) are particularly susceptible to sepsis and experience higher morbidity and mortality rates than younger people. We previously showed that interferon regulatory factor 3 (IRF3) contributes to sepsis path...

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Detalles Bibliográficos
Autores principales: Goswami, Dinesh G, Walker, Wendy E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573150/
https://www.ncbi.nlm.nih.gov/pubmed/34764669
http://dx.doi.org/10.2147/JIR.S335203