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CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27(kip1) Axis

BACKGROUND: Cytochrome P450 2C8 (CYP2C8) gene is one of the members of the cytochrome P450 enzymes (CYPs) gene family. The aim of this study was to reveal the function of CYP2C8 in hepatocellular carcinoma (HCC) and its effect on the sorafenib resistance. METHODS: Differential expression analysis in...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Li, Tian-Man, Luo, Jian-Zhu, Lan, Chen-Lu, Wei, Zhong-Liu, Fu, Tian-Hao, Liao, Xi-Wen, Zhu, Guang-Zhi, Ye, Xin-Ping, Peng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573156/
https://www.ncbi.nlm.nih.gov/pubmed/34765572
http://dx.doi.org/10.2147/JHC.S335425