Cargando…

Structural basis for the inhibition of the Bacillus subtilis c-di-AMP cyclase CdaA by the phosphoglucomutase GlmM

Cyclic-di-adenosine monophosphate (c-di-AMP) is an important nucleotide signaling molecule that plays a key role in osmotic regulation in bacteria. c-di-AMP is produced from two molecules of ATP by proteins containing a diadenylate cyclase (DAC) domain. In Bacillus subtilis, the main c-di-AMP cyclas...

Descripción completa

Detalles Bibliográficos
Autores principales: Pathania, Monisha, Tosi, Tommaso, Millership, Charlotte, Hoshiga, Fumiya, Morgan, Rhodri M.L., Freemont, Paul S., Gründling, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573169/
https://www.ncbi.nlm.nih.gov/pubmed/34678313
http://dx.doi.org/10.1016/j.jbc.2021.101317