Evolutionary selection of alleles in the melanophilin gene that impacts on prostate organ function and cancer risk

BACKGROUND AND OBJECTIVES: Several hundred inherited genetic variants or SNPs that alter the risk of cancer have been identified through genome-wide association studies. In populations of European ancestry, these variants are mostly present at relatively high frequencies. To gain insight into evolut...

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Detalles Bibliográficos
Autores principales: Ermini, Luca, Francis, Jeffrey C, Rosa, Gabriel S, Rose, Alexandra J, Ning, Jian, Greaves, Mel, Swain, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573191/
https://www.ncbi.nlm.nih.gov/pubmed/34754452
http://dx.doi.org/10.1093/emph/eoab026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573191/
https://www.ncbi.nlm.nih.gov/pubmed/34754452
http://dx.doi.org/10.1093/emph/eoab026

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