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Evolutionary selection of alleles in the melanophilin gene that impacts on prostate organ function and cancer risk
BACKGROUND AND OBJECTIVES: Several hundred inherited genetic variants or SNPs that alter the risk of cancer have been identified through genome-wide association studies. In populations of European ancestry, these variants are mostly present at relatively high frequencies. To gain insight into evolut...
Autores principales: | Ermini, Luca, Francis, Jeffrey C, Rosa, Gabriel S, Rose, Alexandra J, Ning, Jian, Greaves, Mel, Swain, Amanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573191/ https://www.ncbi.nlm.nih.gov/pubmed/34754452 http://dx.doi.org/10.1093/emph/eoab026 |
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