IRF2BP2 3′UTR Polymorphism Increases Coronary Artery Calcification in Men

Interferon regulatory factor 2 binding protein 2 (IRF2BP2) suppresses the innate inflammatory response of macrophages. A 9-nucleotide deletion (rs3045215) in the 3′ untranslated region (3′-UTR) of human IRF2BP2 mRNA confers risk of coronary artery disease (CAD) in the Ottawa Heart Genomics Study (OH...

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Detalles Bibliográficos
Autores principales: Vilmundarson, Ragnar O., Duong, An, Soheili, Fariborz, Chen, Hsiao-Huei, Stewart, Alexandre F. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573268/
https://www.ncbi.nlm.nih.gov/pubmed/34760935
http://dx.doi.org/10.3389/fcvm.2021.687645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573268/
https://www.ncbi.nlm.nih.gov/pubmed/34760935
http://dx.doi.org/10.3389/fcvm.2021.687645

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